Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Adicionar filtros








Intervalo de ano
1.
Genet. mol. res. (Online) ; 7(2): 467-475, 2008.
Artigo em Inglês | LILACS | ID: lil-640991

RESUMO

As a contribution towards detecting the genetic effects of low doses of genotoxic physical agents, this paper deals with the consequences of low-dose X-rays in the Aspergillus nidulans genome. The irradiation doses studied were those commonly used in dental clinics (1-5 cGy). Even very low doses promoted increased mitotic crossing-over frequencies in diploid strains heterozygous for several genetic markers including the ones involved in DNA repair and recombination mechanisms. Genetic markers of several heterozygous strains were individually analyzed disclosing that some markers were especially sensitive to the treatments. These markers should be chosen as bio-indicators in the homozygotization index assay to better detect the recombinogenic/carcinogenic genomic effects of low-dose X-rays.


Assuntos
Aspergillus nidulans/efeitos da radiação , Mitose/efeitos da radiação , Troca Genética/efeitos da radiação , Raios X , Aspergillus nidulans/genética , Diploide , Dano ao DNA , Homozigoto , Testes de Mutagenicidade , Mitose/genética , Relação Dose-Resposta à Radiação , Troca Genética/genética
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA